Don't listen to the "my friend" poster below- totally inaccurate. Think about it, if you are part of the layoff your last day isn't until 60 days from the date you are notified that you are being layer off. You will remain active that entire time as you are still an employee meaning you will continue to be a participant in the 401k up until your last day as a Humana employee. Now, if you ARE impacted and decide you want to stop depositing into your 401k you can in fact stop contributing, anyone can choose to stop participating at any time. Just so everyone knows, I am speaking from experience as I have been layed of by Humana in the past and had a 401k at that time.