Takeda Pharmaceutical made sure to slim legacy employees as much as possible.

https://www.bostonglobe.com/business/2018/04/25/shire-takeover-may-take-months-finish/vsmDXRo58xpOF0gIdeuuSI/story.html

When will upper management at Shire realize that employees are the backbone of this company? Some of them are so disconnected with us in our department that I look at one or two of them and think “aren’t we on the same team?” We are given unrealistic... — read more 

When I think of Shire, I picture a boat with no rudder, floating aimlessly with no sense of direction and that’s what this company is going through. There is very little guidance from department heads due to so many changes taking place both in... — read more 

No layoffs right now, they has some layoffs a few months back. I am hearing that Global Drug Safety may be impacted in January or February 2018 time frame - we will see how things play out but I am concerned that this time Shire will cutting much... — read more 

Shire does buy out companies and layoff people in a short amount of time with no offer to transfer within the company.

Not sure about other departments, but Global Drug Safety got layoff about ten to fifteen days ago. It is ex Baxalta. They used us and trashed. Most of us will be gone by October. They did not even offer relocation. Few days ago our positions were... — read more 

Announcement was made to expect HR calls today. Is it Layoff? Are they going to close whole location? Anybody knows what is going on?

We had info as maybe 500 to 600 people will go, plasma sites will close, Thousands Oaks closes or stops Advate, in Switzerland Vonvendi is halted maybe untl 2019. All this is to move the share up? They want to show that the synergies are well in... — read more 

I think that our lovely Shire ship is sinking fast. Just look at multiple high level (and very powerful) folks who left recently - it's very indicative. How about delays with payouts - that itself should be a major red flag that will indicate that... — read more 

I worked myself to the point im having health issues...always there when they needed me...always did the extra. I took this job serious...was proud of it. I was fooled to be a temp. For almost 2 years and a half...overworked underpayed not insured... — read more 

More consolidation will take place in Q2 2016 - possible layoffs

Now that Shire Baxalta merger is looming, you can expect Baxalta to have major RIFs

Over 300 people in Bedminster NJ (former NPS) offices will lose their jobs when Shire closes the NJ operation. People were offered the opportunity to bid on positions in Lexington (very few available in Chesterbrook). Considering that these layoff... — read more 

If you need more details about layoffs / redundancies at Shire just google Cafepharma Shire

I just posted below regarding the La Jolla plant - I wanted to see if Shire had any additional layoffs in 2014 and what the plans for 2015 will be.

Shire Regenerative Medicine laid off staff at the La Jolla plant’s (around 500 people) back in March of 2014. WARN was filed with the state department of employment. Organogenesis who was part of the purchase deal, intended to hire as many of them as... — read more 

Shire is a really bad company to work for. You will eventually be laid off - this company is going nowhere and will either fold or be acquired. The leadership has only one interest - extract as much money for themselves. Salesforce is average, R&D is... — read more 

There has been one (almost two) round of layoffs in ADHD (more to come here, but let's park this for now). One big round of layoffs in GI (possibly more coming). Finally, three BIG rounds of layoffs took place in Renal, the business unit eventually... — read more 

can you post any rumors you know here?

Just go to cafepharma, there is long thread on shire layoffs

SHPGY is doing just fine - do not worry about rumors, we are growing and we have many things in the pipeline..